034 High doses of clopidogrel to overcome genetic resistance: the randomized cross-over CLOVIS-2 study
نویسندگان
چکیده
منابع مشابه
Role of genetic factors on the effect of additional loading doses and two maintenance doses used to overcome clopidogrel hyporesponsiveness.
BACKGROUND AND OBJECTIVE Additional loading doses and higher maintenance doses (MDs) have been used to overcome hyporesponsiveness of clopidogrel. We aimed to investigate whether genetic polymorphisms of two cytochromes (CYP2C19 and CYP2C9) and ABCB1 modify effect of such dose-adjustment strategy. MATERIALS AND METHODS We enrolled 118 patients undergoing elective or acute percutaneous coronar...
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15 صفحه اولRandomized comparison of adjunctive cilostazol versus high maintenance dose clopidogrel in patients with high post-treatment platelet reactivity: results of the ACCEL-RESISTANCE (Adjunctive Cilostazol Versus High Maintenance Dose Clopidogrel in Patients With Clopidogrel Resistance) randomized study.
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ژورنال
عنوان ژورنال: Archives of Cardiovascular Diseases Supplements
سال: 2012
ISSN: 1878-6480
DOI: 10.1016/s1878-6480(12)70430-5